US Patent 8012503 Method of enhancing absorptions of transmucosal administration formulations

Patent 8012503 was granted and assigned to The Chinese University of Hong Kong Chorus on September, 2011 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

The Chinese University of Hong Kong Chorus

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

8012503

Patent Inventor Names

Sing Sum Moses Chow0

Zhong Joan Zuo0

Yan-feng Wang0

Date of Patent

September 6, 2011

Patent Application Number

12017260

Date Filed

January 21, 2008

Patent Primary Examiner

‌

Ernst Arnold

Patent abstract

A method for enhancing absorption of a compound in a medicament that is suitable for administering transmucosally to a subject is conducted in an environment having a suitable pH. The suitable pH is determined based on the ionization constant (dissociation constant) of the compound in water, the solubility of the ionized form of the compound, and the solubility of the non-ionized form of the compound.

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