Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
September 13, 2011
Patent Application Number
11346759
Date Filed
February 2, 2006
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to a method for determining if a test compound, or a mix of compounds, modulates the interaction between two proteins of interest. The determination is made possible via the use of two recombinant molecules, one of which contains the first protein a cleavage site for a proteolytic molecules, and an activator of a gene. The second recombinant molecule includes the second protein and the proteolytic molecule. If the test compound binds to the first protein, a reaction is initiated whereby the activator is cleaved, and activates a reporter gene.
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