Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hans Klingemann0
Date of Patent
October 11, 2011
0Patent Application Number
104562370
Date Filed
June 6, 2003
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
This invention relates to a natural killer cell line termed NK-92 and to NK-92 cell lines that have been modified by transfection with a vector to confer advantageous properties. The invention provides a modified NK-92 cell line that is transfected with a vector encoding a cytokine that promotes the growth of NK-92 cells. In a significant embodiment, the cytokine is interleukin 2. The invention additionally provides a modified NK-92 cell line that is transfected with a vector that expresses a thymidine kinase gene. The invention further provides a modified NK-92 cell line that is transfected with a vector that expresses a β2 micrglobulin.
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