US Patent 8071541 Methods for preparing internally constrained peptides and peptidomimetics

Patent 8071541 was granted and assigned to Aileron Therapeutics on December, 2011 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee

Aileron Therapeutics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

8071541

Date of Patent

December 6, 2011

Patent Application Number

12712089

Date Filed

February 24, 2010

Patent Citations Received

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US Patent 11865160 Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof

Patent Primary Examiner

‌

Cecilia J. Tsang

Patent abstract

The present invention relates to a method for preparing a peptide having a stable, internally constrained alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region and a method of stabilizing an alpha-helical, beta-sheet/beta-turn, 310-helical, or pi-helical region within a peptide structure. The resulting peptides and methods of using them are also disclosed.

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