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US Patent 8071632 Antioxidant inflammation modulators: novel derivatives of oleanolic acid

Patent 8071632 was granted and assigned to Reata Pharmaceuticals, Inc. on December, 2011 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Reata Pharmaceuticals, Inc.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Lester L. Maravetz0

Jack Greiner0

Melean Visnick0

Stephen S. Szucs0

Xin Jiang0

Date of Patent

December 6, 2011

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Patent Application Number

124267910

Date Filed

April 20, 2009

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Patent Citations Received

US Patent 11873320 2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof

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US Patent 12065464 2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof

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US Patent 11911395 Methods of treating obesity using antioxidant inflammation modulators

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US Patent 11993574 Pyrazole and imidazole compounds for inhibition of IL-17 and RORgamma

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US Patent 12060340 Cysteine-dependent inverse agonists of nuclear receptors ROR-gamma/ROR-gamma-t and methods of treating diseases or disorders therewith

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US Patent 11919838 Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at C-17

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Patent Primary Examiner

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Patent abstract

Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

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