Patent 8075780 was granted and assigned to Millipore Sigma on December, 2011 by the United States Patent and Trademark Office.
The present invention is an ultrafiltration (UF) membrane having a nominal molecular weight cut off (NMWCO) of from about 0.5 KD to about 10 KD wherein the membrane surfaces have a charge that is either positive or negative. The present invention is also a method of using the charged UF membrane to purify and concentrate synthetic biological molecules by using the charged surface either to repel the synthetic biomolecules retaining them in the retentate or to attract the synthetic biomolecules preferentially for filtration through the membrane.