Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Eric Smith0
Nicholas J. Papadopoulos0
Sean Stevens0
Tammy T. Huang0
Allen Radin0
Ashique Rafique0
Gang Chen0
James P. Fandl0
...
Date of Patent
December 20, 2011
0Patent Application Number
127800060
Date Filed
May 14, 2010
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.
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