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US Patent 8088376 Fc variants with altered binding to FcRn

Patent 8088376 was granted and assigned to Xencor on January, 2012 by the United States Patent and Trademark Office.

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US Patent 12128101 Dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)
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US Patent 12110324 Antigen binding molecules targeting thymic stromal lymphopoietin (TSLP)
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US Patent 12012448 High concentration anti-C5 antibody formulations
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US Patent 11993644 Antigen binding molecules targeting SARS-CoV-2
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US Patent 11987617 Antibodies that target HIV GP120 and methods of use
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US Patent 11987616 Antigen binding molecules targeting SARS-CoV-2
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US Patent 11981725 Antigen binding molecules targeting SARS-CoV-2
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US Patent 11932685 Fc variants with altered binding to FcRn
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US Patent 11912778 Methods of engineering transferrin receptor binding polypeptides
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US Patent 11858991 LAG-3-binding molecules and methods of use thereof
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US Patent 11858980 Engineered polypeptides and uses thereof
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US Patent 11840571 Methods of using bispecific molecules having immunoreactivity with PD-1 and CTLA-4
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Patent abstract

The present application relates to a variant Fc region comprising the double mutation 428L/434S that increases serum half-life and the numbering is according to the EU index.

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US Patent 11655290 Anti-CSP antibodies
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US Patent 11655285 Human immunodeficiency virus neutralizing antibodies
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US Patent 08088376 Fc variants with altered binding to FcRn US Patent 8088376 Fc variants with altered binding to FcRn

Infobox
Patent Number
0808837600
Patent Number
808837600
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Infobox
Is a
Patent
Patent
0
Current Assignee
Xencor
Xencor
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
080883760
Date of Patent
January 3, 2012
0
Patent Application Number
130081650
Date Filed
January 18, 2011
0
Patent Primary Examiner
‌
Chun Dahle
0
Edits on 23 Sep, 2022
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edited on 23 Sep, 2022
Infobox
Is a
Patent
Patent
0
Current Assignee
Xencor
Xencor
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
080883760
Date of Patent
January 3, 2012
0
Patent Application Number
130081650
Date Filed
January 18, 2011
0
Patent Primary Examiner
‌
Chun Dahle
0

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