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US Patent 8106022 Carbohydrate conjugates as delivery agents for oligonucleotides

Patent 8106022 was granted and assigned to Alnylam Pharmaceuticals on January, 2012 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Alnylam Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

8106022

Patent Inventor Names

Jayaprakash K. Narayanannair0

Martin Maier0

Muthiah Manoharan0

Kallanthottathil G. Rajeev0

Date of Patent

January 31, 2012

Patent Application Number

12328528

Date Filed

December 4, 2008

Patent Citations Received

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US Patent 12129466 Compounds and methods for modulating UBE3A-ATS

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US Patent 12059468 Carbohydrate conjugates as delivery agents for oligonucleotides

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US Patent 12060381 Methods for purification of messenger RNA

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US Patent 12084702 Methods for purification of messenger RNA

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US Patent 12091666 Xanthine dehydrogenase (XDH) iRNA compositions and methods of use thereof

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US Patent 12116573 Targeting ligands for therapeutic compounds

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US Patent 12121592 Lipid nanoparticle compositions and methods for mRNA delivery

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Patent Primary Examiner

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Patrick Lewis

Patent abstract

The present invention provides iRNA agents comprising at least one subunit of the formula (I):

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