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US Patent 8110658 Peptide fragments for inducing synthesis of extracellular matrix proteins

Patent 8110658 was granted and assigned to HELIX BIOMEDIX on February, 2012 by the United States Patent and Trademark Office.

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Current Assignee
HELIX BIOMEDIX
HELIX BIOMEDIX
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8110658
Date of Patent
February 7, 2012
Patent Application Number
11811876
Date Filed
June 12, 2007
Patent Primary Examiner
‌
David Lukton
Patent abstract

Short biologically active tetrapeptides are disclosed that are comprised of the sequences GxxG and PxxP where G (glycine) and P (proline) are maintained and x is a variable amino acid. The peptides can be used singly or in combination to stimulate production of extracellular matrix proteins in skin. A rapid, low-cost method of producing heterogenous formulations of tetrapeptides is disclosed.

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