A cardiac stimulation device has a plurality of electrodes that deliver therapeutic electrical stimulation to the heart. At least one electrode is designated a cathode that cathodically induces depolarization of the surrounding heart tissue. At least one electrode is designated an anode. The device is configured, through one or more of electrode size, electrode configuration, electrode arrangement, cathode/anode number and pulse delivery circuitry, to induce depolarization of the heart tissue in the area of the at least one anode electrode, thereby resulting in greater depolarization of the heart tissue with reduced power consumption.