Patent 8152999 was granted and assigned to Wisconsin Alumni Research Foundation on April, 2012 by the United States Patent and Trademark Office.
The present invention provides counter flow cascade separation systems useful to separate solute/solute pairs present in a solvent. The separation systems include a series of interconnected stages with each stage comprising a diafilter preferentially permeable for one solute. Solute/solute pairs are preferentially separated by the diafilter into permeate and retentate flows. Stages are combined to form separation systems capable of operation approaching an ideal cascade.