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US Patent 8178490 Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof

Patent 8178490 was granted and assigned to Rempex Pharmaceuticals on May, 2012 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Rempex Pharmaceuticals
Rempex Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
81784900
Patent Inventor Names
Tomasz Glinka0
Keith A. Bostian0
Olga Rodny0
Robert I. Higuchi0
Brian Eastman0
Chi Ching Mak0
Chun Chow0
David M. Wallace0
...
Date of Patent
May 15, 2012
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Patent Application Number
126133290
Date Filed
November 5, 2009
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Patent Primary Examiner
‌
Cecilia J. Tsang
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Patent abstract

Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.

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