US Patent 8188248 Nucleic acids encoding interleukin-12P40 variants with improved stability
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Patent abstract
Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
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US Patent 08188248 Nucleic acids encoding interleukin-12P40 variants with improved stability US Patent 8188248 Nucleic acids encoding interleukin-12P40 variants with improved stability
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Patent Number
0818824800
Patent Number
818824800
Edits on 29 Apr, 2023
Golden AI
Infobox
Is a
Patent Jurisdiction
Patent Number
081882480
Date of Patent
May 29, 2012
0Patent Application Number
129617330
Date Filed
December 7, 2010
0Patent Primary Examiner
Edits on 23 Sep, 2022
Golden AI
Infobox
Is a
Patent Jurisdiction
Patent Number
081882480
Date of Patent
May 29, 2012
0Patent Application Number
129617330
Date Filed
December 7, 2010
0Patent Primary Examiner
Edits on 14 Dec, 2021
Golden AI
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Infobox (+7 properties)
US Patent 08188248 Nucleic acids encoding interleukin-12P40 variants with improved stability
Infobox
Is a
Patent jurisdiction
Patent number
08188248
Date of patent
May 29, 2012
Patent application number
12961733
Date Filed
December 7, 2010
Patent primary examiner
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