Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tammy T. Huang0
Allen Radin0
Ashique Rafique0
Eric Smith0
Gang Chen0
James P. Fandl0
Jeanette L. Fairhurst0
Joel H. Martin0
...
Date of Patent
June 5, 2012
Patent Application Number
13286261
Date Filed
November 1, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.
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