Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael J. Tolentino0
Samuel J. Reich0
Date of Patent
June 5, 2012
Patent Application Number
12952046
Date Filed
November 22, 2010
Patent Citations Received
Patent Primary Examiner
Patent abstract
RNA interference using small interfering RNAs which are specific for the ICAM-1 gene inhibits expression of this gene. Diseases which involve ICAM-1-mediated cell adhesion, such as inflammatory and autoimmune diseases, diabetic retinopathy and other complications arising from type I diabetes, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.
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