Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 26, 2012
Patent Application Number
11597509
Date Filed
March 11, 2005
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to a method for the expansion and differentiation of haematopoietic stem cells into enucleated erythrocytes, in two steps: a first step in a culture medium, where cell proliferation and erythmid differentiation are induced in the presence of growth factors, and a second step modeling a reconstitution of the microenvironment, substantially without erythropoietin (EPO). Optionally, the method of culture may comprise an intermediate step, with haematopoietic growth factors.
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