Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christoph Rader0
Subhash C. Sinha0
Carlos F. Barbas0
Richard A. Lerner0
Date of Patent
August 28, 2012
0Patent Application Number
102783640
Date Filed
October 22, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides antibody targeting compounds in which the specificity of the antibody has been reprogrammed by covalently or noncovalently linking a targeting agent to the combining site of an antibody. By this approach, the covalently modified antibody takes on the binding specificity of the targeting agent. The compound may have biological activity provided by the targeting agent or by a separate biological agent. Various uses of the invention compounds are provided.
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