Golden has been acquired by ComplyAdvantage.Read about it here ⟶

‌

US Patent 8349311 Mutant interleukin-2 (IL-2) polypeptides

Patent 8349311 was granted and assigned to Massachusetts Institute of Technology on January, 2013 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors Activity

Is a

Patent attributes

Current Assignee

Massachusetts Institute of Technology

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Balaji M. Rao0

Douglas A. Lauffenburger0

Karl Dane Wittrup0

Date of Patent

January 8, 2013

Patent Application Number

13088045

Date Filed

April 15, 2011

Patent Citations Received

US Patent 12091440 IL2 and peptide-MHC complex fusion proteins and methods of use thereof

0

US Patent 11779632 IL-2 muteins and uses thereof

US Patent 11945852 IL-2 muteins and uses thereof

0

US Patent 11965008 IL-2 muteins and uses thereof

0

US Patent 11981715 Tissue targeted immunotolerance with a CD39 effector

0

US Patent 12084484 Interleukin-2 agents and uses thereof

0

US Patent 12091441 Partial agonists of interleukin-2

0

Patent Primary Examiner

Patent abstract

The present invention relates to IL-2 mutants with increased affinity for the IL-2 alpha-receptor subunit (IL-2Rα). The invention thus includes IL-2 mutants with improved biological potency. The invention also includes methods for directed evolution of IL-2α using yeast surface display to generate mutants with increased affinity for IL-2Rα.

Timeline

No Timeline data yet.

Further Resources

Title

Author

Link

Type

Date

No Further Resources data yet.

References

Find more entities like US Patent 8349311 Mutant interleukin-2 (IL-2) polypeptides

Use the Golden Query Tool to find similar entities by any field in the Knowledge Graph, including industry, location, and more.

Open Query Tool

Golden Query Tool