A drain snake device having a rotatable handle crank at one end and an interlocking opposite end. The interlocking end is uniquely attachable to a corresponding attachment end portion of a disposable elongated snake segment. A slidable sleeve, that moves axially along the distal end of the handle between a locking position and a release position, fully engages or releases the disposable snake segment, respectively, and also simultaneously allows or blocks rotation of the handle crank, respectively. A kit containing a reusable handle and two or more uniquely corresponding snake segments is also provided.