Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Umesh S. Muchhal0
John R. Desjarlais0
Matthew J. Bernett0
Sher Bahadur Karki0
Duc-Hanh Thi Nguyen0
Gregory Alan Lazar0
John O. Richards0
Date of Patent
March 12, 2013
0Patent Application Number
124418850
Date Filed
September 18, 2007
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present disclosure describes antibodies that target HM1.24. In various aspects, the antibodies have specific CDR, variable, or full length sequences, have modifications with the parent antibody, or include at least one one modification relative to a parent antibody that alters affinity to an FcγR or alters effector function as compared to the parent antibody. Nucleic acids encoding the antibodies and methods of using the antibodies are also disclosed.
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