Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Roger L. Kaspar0
Attila A. Seyhan0
Brian H. Johnston0
Heini Ilves0
Alexander V. Vlassov0
Date of Patent
April 23, 2013
Patent Application Number
13039100
Date Filed
March 2, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) that are useful for inhibition of viral-mediated gene expression. Small interfering RNAs as described herein can be used in methods of treatment of HCV infection. ShRNA and siRNA constructs targetING the internal ribosome entry site (IRES) sequence of HCV are described.
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