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US Patent 8450467 Carbohydrate conjugates as delivery agents for oligonucleotides

Patent 8450467 was granted and assigned to Alnylam Pharmaceuticals on May, 2013 by the United States Patent and Trademark Office.

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Patent

Patent attributes

Current Assignee

Alnylam Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

8450467

Date of Patent

May 28, 2013

Patent Application Number

13326203

Date Filed

December 14, 2011

Patent Citations Received

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US Patent 12121592 Lipid nanoparticle compositions and methods for mRNA delivery

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US Patent 12084655 Packaging oligonucleotides into virus-like particles

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US Patent 12084702 Methods for purification of messenger RNA

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US Patent 12116573 Targeting ligands for therapeutic compounds

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US Patent 11666653 Carbohydrate conjugates as delivery agents for oligonucleotides

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US Patent 11692189 Methods for purification of messenger RNA

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US Patent 11851655 Compositions and methods for modulating apolipoprotein (a) expression

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US Patent 11873490 Antisense oligomers for treatment of conditions and diseases

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Patent Primary Examiner

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Patrick Lewis

Patent abstract

The present invention provides iRNA agents comprising at least one subunit of the formula (I):

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