US Patent 8487134 Process for the synthesis of amphetamine derivatives
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Patent abstract
The invention relates to processes for preparing acylated amphetamine, methamphetamine and dexamphetamine derivatives by reacting the parent amine with the to be-coupled acid or a salt of the to-be coupled acid which acid is optionally protected, in the presence of an alkylphosphonic acid anhydride as coupling agent and, if the acid was protected then cleaving the protecting group(s), in a one-pot reaction or in two or more separate steps.
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Patent Inventor Names
Andreas Meudt0
Jason Helmke0
Paul Meek0
Quofang Qiu0
Richard Wisdom0
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US Patent 08487134 Process for the synthesis of amphetamine derivatives US Patent 8487134 Process for the synthesis of amphetamine derivatives
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Patent Number
08487134
Patent Number
8487134
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US Patent 08487134 Process for the synthesis of amphetamine derivatives
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Is a
Patent jurisdiction
Patent number
08487134
Date of patent
July 16, 2013
Patent application number
13122893
Date Filed
October 9, 2008
Patent primary examiner
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