A micro-fluidic valve system is provided which includes a micro-fluidic valve actuator apparatus, a fluid distribution manifold and a micro-fluidic POD apparatus. The POD apparatus includes a POD housing that defines an interior central passage extending from a distal mounting end of the housing to a proximal portion thereof. The POD apparatus further includes a stator device disposed in the interior central passage, and includes a distal stator face that cooperates with an opening in the distal mounting end to define a gasket receptacle. A relatively thin, elastomeric gasket member is disposed in the gasket receptacle of the housing in abutting contact between the stator and a communication face of the manifold. A fluid-tight seal is then formed between each respective stator communication port of the stator device and a corresponding manifold communication port of the manifold.