Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Nikolai Naryshkin0
Charles Romfo0
Ellen Welch0
Sergey V. Paushkin0
Date of Patent
January 21, 2014
0Patent Application Number
129945170
Date Filed
May 27, 2009
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides nucleic acid constructs, methods for identifying and validating compounds that increase the inclusion of exon 7 of SMN2 into mRNA transcribed from the SMN2 gene, compounds and pharmaceutical compositions that increase levels of SMN protein produced from the SMN2 gene, and methods for use thereof in treating of SMA.
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