US Patent 8637324 Bead incubation and washing on a droplet actuator
Patent 8637324 was granted and assigned to Advanced Liquid Logic on January, 2014 by the United States Patent and Trademark Office.
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The present invention relates to bead incubating and washing on a droplet actuator. Methods for incubating magnetically responsive beads that are labeled with primary antibody, a sample (i.e., analyte), and secondary reporter antibodies on a magnet, on and off a magnet, and completely off a magnet are provided. Also provided are methods for washing magnetically responsive beads using shape-assisted merging of droplets. Also provided are methods for shape-mediated splitting, transporting, and dispensing of a sample droplet that contains magnetically responsive beads. The apparatuses and methods of the invention provide for rapid time to result and optimum detection of an analyte in an immunoassay.
US Patent 08637324 Bead incubation and washing on a droplet actuator US Patent 8637324 Bead incubation and washing on a droplet actuator
US Patent 08637324 Bead incubation and washing on a droplet actuator
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