Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hsing-Wen Sung0
Hosheng Tu0
Ko-Jie Chen0
Min-Fan Chung0
Po-Yuan Cheng0
Zi-Xian Liao0
Date of Patent
March 4, 2014
0Patent Application Number
136829290
Date Filed
November 21, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention discloses a pharmaceutical composition of pH-sensitive liposome nanoparticles for lodging in a target tissue cell in situ of an animal subject, the nanoparticles comprising a proton-releasing photosensitive compound that releases protons upon photolysis, wherein the compound is in vesicles of the liposomes. A light or UV light is provided to induce the photosensitive compound to release the protons, thus the released protons causing the pH-sensitive liposome to decompose.
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