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US Patent 8691184 Bcl-2/Bcl-xL inhibitors and therapeutic methods using the same

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Liu Liu0

Longchuan Bai0

Shaomeng Wang0

Xiaoqin Li0

Haibin Zhou0

Angelo Aguilar0

Chao-Yie Yang0

Donna McEachem0

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Date of Patent

April 8, 2014

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Patent Application Number

133567630

Date Filed

January 24, 2012

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Patent Citations Received

US Patent 11865123 Methods of inhibiting pathological angiogenesis

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US Patent 11980616 Treating liver disease by selectively eliminating senescent cells

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US Patent 11963957 Treating cardiovascular disease by selectively eliminating senescent cells

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US Patent 12118414 BCL-2 proteins degraders for cancer treatment

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Patent Primary Examiner

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Patent abstract

Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.

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