In a method of interference rejection combining (IRC) for mitigating interference in received signals in the frequency domain for a telecommunication system, selecting (S 10) a sub-group of frequencies of a received signal, determining (S20) a joint representation of a covariance matrix for the interference plus noise for at least one time slot of the received signal for the selected sub-group of frequencies, determining (S30) a channel estimate based on at least one pilot symbol of said at least one time slot. Finally, determining (S40) IRC coefficients in the frequency domain for each symbol of said at least one time slot based on said determined joint representation of the covariance matrix and said determined channel estimate.