US Patent 8715964 Expression of IL-12 family heterodimers
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Patent abstract
The present invention provides methods of improving the levels and stability of expression of interleukin-12 family cytokine polypeptides by expressing the alpha and beta subunits of the polypeptides at their determined relative molar ratios that increase the levels and stability of expression of the heterodimer, e.g., in comparison to heterodimer expressed at an equimolar ratio.
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Patent Inventor Names
Barbara K. Felber0
George N. Pavlakis0
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US Patent 08715964 Expression of IL-12 family heterodimers US Patent 8715964 Expression of IL-12 family heterodimers
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Patent Number
087159640
Patent Number
87159640
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Patent Jurisdiction
Patent Number
087159640
Date of Patent
May 6, 2014
0Patent Application Number
129920770
Date Filed
May 11, 2009
0Official Website
Patent Primary Examiner
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US Patent 08715964 Expression of IL-12 family heterodimers
Infobox
Is a
Patent jurisdiction
Patent number
08715964
Date of patent
May 6, 2014
Patent application number
12992077
Date Filed
May 11, 2009
Patent primary examiner
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