Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Timo Kars van den Berg0
Date of Patent
May 20, 2014
0Patent Application Number
129377640
Date Filed
April 23, 2009
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g. cancer cells or virus-infected cells, by the host's immune system. Provided is a composition comprising (i) a therapeutic compound that can trigger a host's immune effector cells against an aberrant cell, such as a therapeutic antibody, and (ii) at least one agent capable of reducing or preventing inhibitory signal transduction initiated via SIRPalpha.
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