Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Abhijit Suresh Bhat0
Alice Lee0
Curt William Bradshaw0
David Tumelty0
Lauren Diane Wood0
Olivier Alexandre Laurent0
Richard Ryan Preston0
Wei Hong Yu0
Date of Patent
June 3, 2014
0Patent Application Number
133053540
Date Filed
November 28, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to Multifunctional Antibody Conjugates, comprising an antibody or antigen binding portion thereof, comprising at least a fragment of a light chain constant kappa region (CLκ) comprising K188 according to Kabat numbering; a linker comprising the formula X-Y-Z, wherein Z is a group is covalently connected to the antibody through the side chain of K188, Y is a linear or branched biologically compatible connecting chain, and X is a group covalently connected to at least one Effector Moiety.
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