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US Patent 8741648 Reprogramming T cells and hematopoietic cells

Patent 8741648 was granted and assigned to Cellular Dynamics International on June, 2014 by the United States Patent and Trademark Office.

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Patent abstract

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.

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