A tire pressure adjustment method and system is provided. The method includes receiving from a plurality of sensors in a vehicle, tread depth data associated with tread depths at multiple points on a tire tread comprised by a tire on the vehicle. The tread depth data is analyzed. A tire pressure value for an internal portion of the tire is determined based on results of the analysis. The tire pressure value is associated with modifying a group of tread depths during operation of the vehicle. In response, a command signal is generated. The command signal is configured to command a tire pressure modification device to adjust a current tire pressure value of the internal portion of the tire to the determined tire pressure value. The command signal is transmitted to the tire pressure modification device resulting in the current tire pressure value being adjusted to determined tire pressure value.