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US Patent 8926967 Intraventricular enzyme delivery for lysosomal storage diseases

Patent 8926967 was granted and assigned to Genzyme on January, 2015 by the United States Patent and Trademark Office.

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Patent abstract

Lysosomal storage diseases can be successfully treated using intraventricular delivery of the enzyme which is etiologically deficient in the disease. The administration can be performed slowly to achieve maximum effect. Surprisingly, effects are seen on both sides of the blood-brain barrier, making this an ideal delivery means for lysosomal storage diseases which affect both brain and visceral organs.

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