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US Patent 8945868 Methods and compositions for modification of a HLA locus

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Michael C. Holmes0

Fyodor Urnov0

Jeffrey C. Miller0

Laurence J. N. Cooper0

Philip D. Gregory0

Trevor Collingwood0

Andreas Reik0

Edward J. Rebar0

Date of Patent

February 3, 2015

Patent Application Number

13188417

Date Filed

July 21, 2011

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US Patent 11872248 Nucleic acids encoding chimeric receptor comprising NKP30 receptor and CD28 and CD3 zeta domains and human T cell containing

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Patent Primary Examiner

Patent abstract

Disclosed herein are methods and compositions for modulating the expression of a HLA locus or for selectively deleting or manipulating a HLA locus or HLA regulator.

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