Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 17, 2015
Patent Application Number
13574504
Date Filed
January 21, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a pharmaceutically acceptable carrier, suitably a carrier for oral or nasal administration. Also provided are methods of enhancing immune responses, in particular antibody immune response and suitably an IgA response, by administering the vaccine vectors or compositions disclosed herein to a subject.
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