Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David J. Reczek0
Paul Saftig0
Christine T. DeMaria0
Date of Patent
February 24, 2015
0Patent Application Number
125993930
Date Filed
May 9, 2008
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention is directed to methods of producing a polypeptide or a variant thereof, wherein the polypeptide or variant thereof is dependent on LIMP-2 for trafficking, localization, stabilization and/or sorting of the polypeptide in the cell. In general, the methods comprise culturing a lysosomal integral membrane protein II (LIMP-2) deficient cell which expresses the polypeptide or the variant thereof under conditions in which the polypeptide or the variant thereof is produced.
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