Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Wataru Hamaguchi0
Yohei Koganemaru0
Isao Kinoyama0
Osamu Kaneko0
Ryuichi Sekioka0
Takehiro Miyazaki0
Takuya Washio0
Date of Patent
February 24, 2015
0Patent Application Number
139569240
Date Filed
August 1, 2013
0Patent Citations Received
Patent Primary Examiner
Patent abstract
To provide an excellent agent for preventing or treating dementia and schizophrenia based on serotonin 5-HT5A receptor regulating action, it was found that a tetrahydroisoquinoline derivative characterized by a structure in which an acylguanidino group binds to a N atom of a tetrahydroisoquinoline ring or the like, and a cyclic group binds to an unsaturated ring has a potent 5-HT5A receptor regulating action and an excellent pharmacological action based on the regulating action and also discovered that the tetrahydroisoquinoline derivative is useful as an agent for treating or preventing dementia, schizophrenia, and the like, whereby the present invention has been completed.
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