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US Patent 8987443 Processes and intermediates for making a JAK inhibitor

Patent 8987443 was granted and assigned to Incyte on March, 2015 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Dengjin Wang0

Ganfeng Cao0

Michael Xia0

Pingli Liu0

Yongzhong Wu0

Date of Patent

March 24, 2015

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Patent Application Number

141977010

Date Filed

March 5, 2014

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Patent Citations Received

US Patent 11905292 Process and intermediates for preparing a JAK inhibitor

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US Patent 12071439 Process and intermediates for preparing a JAK inhibitor

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US Patent 11992490 Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP)

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US Patent 11685731 Processes of preparing a JAK1 inhibitor

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US Patent 11744832 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors

US Patent 11957661 JAK1 pathway inhibitors for the treatment of vitiligo

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US Patent 11905275 Bipyrazole derivatives as JAK inhibitors

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US Patent 11833152 JAK1 pathway inhibitors for the treatment of cytokine-related disorders

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Patent Primary Examiner

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Patent abstract

This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.

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