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US Patent 8993545 Carbonate prodrugs and methods of using the same

Patent 8993545 was granted and assigned to Acorda Therapeutics, Inc. on March, 2015 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant
Acorda Therapeutics, Inc.
Acorda Therapeutics, Inc.
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Current Assignee
Acorda Therapeutics, Inc.
Acorda Therapeutics, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
89935450
Patent Inventor Names
Keith R. Bley0
Naweed Muhammad0
Date of Patent
March 31, 2015
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Patent Application Number
142526830
Date Filed
April 14, 2014
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Patent Primary Examiner
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Kristin Vajda
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Patent abstract

The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.

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