Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hillary Overholser0
Jennifer Woodell-May0
Date of Patent
April 21, 2015
Patent Application Number
13099087
Date Filed
May 2, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
Methods, apparatus, and compositions related to generating and using thrombin. Methods include preparing a solution comprising thrombin by precipitating fibrinogen from a liquid comprising whole blood or a blood fraction. Precipitated fibrinogen is removed from the liquid to form a post-precipitation liquid that is incubated with calcium and a plurality of beads to form a clot. A solution comprising thrombin is separated from the clot. Thrombin prepared thereby can be used as a tissue sealant and in methods of applying a tissue sealant to subject, including application of an autologous tissue sealant.
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