Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Harald Rau0
Torben Lessmann0
Date of Patent
June 23, 2015
Patent Application Number
13574092
Date Filed
January 21, 2011
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof, comprising a drug linker conjugate D-L, wherein D being a biologically active moiety containing an aliphatic amine group is conjugated to one or more polymeric carriers via dipeptide-containing linkers L. Such carrier-linked prodrugs achieve drug releases with therapeutically useful half-lives. The invention also relates to pharmaceutical compositions comprising said prodrugs and their use as medicaments.
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