Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
September 22, 2015
0Patent Application Number
129404250
Date Filed
November 5, 2010
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Provided herein are ophthalmically acceptable pharmaceutical compositions comprising a PRG4 inducing compound in combination with PRG4 (including a lubricant fragments, homologs, or isoforms thereof), and methods of using the same. The PRG4 inducing compound in the pharmaceutical composition of the present invention upregulates PRG4 expression and localization in the ocular surface for efficient surface boundary lubrication. In some instances, pharmaceutical compositions described herein are utilized for treating ophthalmic conditions, e.g., ocular boundary deficiency and symptoms associated therewith.
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