Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 13, 2015
Patent Application Number
13934489
Date Filed
July 3, 2013
Patent Citations Received
Patent Primary Examiner
Patent abstract
Disclosed herein are compounds, compositions and methods for modulating splicing of a selected target mRNA. Further provided are uses of the disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Methods of enhancing cellular uptake, modulating tissue distribution and enhancing pharmacological activity of RNase H-independent antisense oligonucleotides are also provided.
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