Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 27, 2015
0Patent Application Number
136350900
Date Filed
March 25, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to a polypeptide, or antigenic portion thereof, wherein the polypeptide is selected from a) MUC16 ectodomain polypeptide, b) MUC16 cytoplasmic domain polypeptide, and c) MUC16 extracellular domain polypeptide that contains a cysteine loop polypeptide. The invention's antibodies and compositions containing them are useful in diagnostic and therapeutic applications for diseases in which MUC16 is overexpressed, such as cancer.
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