Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 3, 2015
0Patent Application Number
135203380
Date Filed
December 30, 2010
0Patent Citations Received
Patent Primary Examiner
Patent abstract
E. coli proteins have been identified that are useful as carrier proteins to improve a response to a polysaccharide immunogen conjugated to such protein. In particular, AcfD precursor protein (orf3526 polypeptide), Flu antigen 43 protein (orf1364 polypeptide), and Sel1 repeat-containing protein (upec-5211 polypeptide) have been shown to be effective. Additionally, these E. coli proteins can enhance the immune response to glucans, particularly fungal glucans.
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