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US Patent 9175266 Enhancement of natural killer (NK) cell proliferation and activity

Patent 9175266 was granted and assigned to Gamida Cell on November, 2015 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Gamida Cell
Gamida Cell
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Current Assignee
Gamida Cell
Gamida Cell
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
91752660
Date of Patent
November 3, 2015
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Patent Application Number
139462660
Date Filed
July 19, 2013
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Patent Primary Examiner
‌
Robert Mondesi
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Patent abstract

Methods of ex-vivo culture of natural killer (NK) cells are provided and, more particularly, methods for enhancing propagation and/or functionality of NK cells by treating the cells with an aryl hydrocarbon antagonist in combination with cytokines driving NK cell proliferation. Also envisioned are compositions comprising cultured NK cells and therapeutic uses thereof.

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