A reciprocating saw having a clamping arrangement with a clamp support base, a first locking member and a release lever. The clamp support base defines a first blade slot that is configured to receive a saw blade therein. The first locking member is movable between a disengaged position, which does not inhibit withdrawal of the saw blade from the first blade slot, and an engaged position that inhibits withdrawal of the saw blade from the first blade slot. The release lever is pivotally coupled to the clamp support base and coordinates movement of the first locking member.